Showing posts with label FDA. Show all posts
Showing posts with label FDA. Show all posts

Thursday, January 17, 2008

More Medical Questioning: Cough & Cold Meds

Okay, so I've written about the vaccination thing. I have my reservations. And questioning vaccinations is a countercultural thing, certainly. The FDA doesn't readily give statistics on deaths from vaccinations, and if they did, it wouldn't be reported in the media. So consider this, from CNN:

In 2007, the FDA completed a review that found there were 54 reported child deaths from decongestants and 69 from antihistamines between 1969 and fall 2006.

It is part of the ever-increasing hype about over-the-counter (OTC) medications. In the past several years, we have seen Phenylpropylalamine pulled completely as a decongestant because some people who were abusing it had heart attacks. Then, we have witnessed as Pseudoephedrine (which has always had mild-to-serious heart problems as a side effect--it makes my heart race horribly; I can't take it) has been restricted, put under lock & key, anyone who wishes to purchase it subjected to a near background-check, and now gradually it is being replaced by Phenylephrine--so that we don't go make Meth out of it. And now we're being told that none of it is safe or (possibly) effective.

Well, I don't particularly want to give a child under 2 all of these drugs anyway. And when I do use medicines, even for myself, I tend to use moderate doses, I do not tend to re-dose on schedule, usually waiting at least 6 hours--really as the symptoms dictate, and I tend to wait until the symptoms are really uncomfortable before dosing. So I am not a pill-poppin' momma by any means. But I do think that there is a little too much hysteria in this case. I believe that what is happening is that the safest stuff is being taken off the market, leading to more prescriptions & doctor's visits, and also leading to rash actions--perhaps the administration of a larger dose to a smaller child out of ignorance. But mostly, I believe that this is inspiring false panic.

Consider: there were 54 reported child deaths from decongestants and 69 from antihistamines between 1969 and fall 2006. Okay, let's do the math. That means that in 37 years, of all of the millions of children who received multiple doses several times a year, 54 children died of decongestants and 69 died from antihistamines. That's 1.46 deaths per year from decongestants and 1.86 from antihistamines. Most were in children under 2 years. Well, for starters, take the fact that as long as I can remember, the package labels said, "under 2 consult a doctor" or "not to be given to children under 2." Then, control for overdosing (I was twice given overdoses of cold medicines when I was young--once I was under 4 years) and re-dosing too soon, or too may times in a 24 hour period. Consider that two medicines containing the same drug or different ones in the same category may have been administered simultaneously. Then (and only then) consider the possibility of allergic reactions. How many people do you think died of peanut allergies in the same time frame? Perhaps we should remove peanuts from the market. Or strawberries. Or milk. Now consider that they group "decongestants" together for the purpose of the analysis and "antihistamines." Well, let's see. . . In the time frame mentioned, at least 3 different decongestants were available, one of which has been taken off the market and one is increasingly difficult to get. So which one(s) caused the deaths? As for antihistamines, I can name Diphenhydramine, Chlorpheniramine Maleate and Brompheniramine Maleate off the top of my head. Again, to which one(s) are they attributing the deaths? And why was it necessary to group them all together? Hyperbole? To make their results statistically significant? And why are they vilifying cough meds, too?

Let me reiterate. . . I am cautious about medicines. Very cautious. Others may not be. If they are not effective, that's different. But why are the same people who say that vaccinations are unequivocally safe trying to scare me about my medicine cabinet?